The Donorregister resorts under the Ministry of Health, Welfare and Sport.

The Donorregister was set up in 1998 to implement the Dutch Organ Donation Act (Wet op de orgaandonatie). This act states that all people age twelve and older residing in the Netherlands, can have their wishes regarding organ and tissue donation registered in the Donorregister. Registration provides clarity and certainty for everyone involved.

The Dutch Organ Donation Act expressly forbids the trading of organs and tissues and ensures that the available organs and tissues are allocated and distributed fairly.